After a lonely boyhood, and the painful ordeal of his schooldays, Philip's yearning for adventure takes him to Germany and later Paris where he tries to make his mark as an artist before returning to London to study medicine. Here, a tortured and one-sided love affair with Mildred, a vulgar yet irresistible waitress, changes the course of his life for ever.

Commenting later on the novel’s autobiographical aspects, Maugham recalled how in writing the book he mingled fact and fiction and 'found myself free from the pains and unhappy recollections that had tormented me'.However, like Dickens’s David Copperfield to which it is often compared, Of Human Bondage goes far beyond autobiography, and is Maugham’s most ambitious and unsparing novel, revealing the author’s undoubted gift for storytelling as he explores the timeless theme of human freedom - freedom to act, to think and to love.