In the 21st century, the once-glittering Neo-Tokyo lies in ruins, leveled in minutes by the infinite power of the child psychic giant, Akira. Now a wasteland of rubble and anarchy, the Great Tokyo Empire rises, a ragtag group of zealots and crazies who worship and fear Akira and his mad prime minister, Tetsuo, an angry teen with immense powers of his own - and equally immense twisted ambitions.

The planet at large is not taking the threat lying down, however, and the might of the world is ready to take on the Empire, but will technology's most advanced weaponry be enough to destroy Akira - and is Tetsuo an ever greater threat?