In 2019, Aahna "Ash" Ashina was the LAPD's most efficient and feared Blade Runner. Two decades later and Ash has lives 'off-grid' as fugitive outlaw helping Replicants escape their enslaved servitude and survive undetected on Earth.

Now, in 2039, Niander's own personal assistant, Luv, has become the first Replicant to be accepted into the Blade Runner unit, but she has a secret agenda, find Cleo, the daughter of industrialist Alexander Selwyn whom Ash helped to escape 20 years earlier.

Now, as Ash's past and future collide, her astonishing story finally concludes as she faces her greatest challenge yet: saving the city she loves from the insane machinations of Niander Wallace, heir of the Tyrell empire. It's up to Ash to keep the truth about the Replicant miracle (seen in Blade Runner 2049) a secret, and to fulfill the pact she made years ago to those she loves most. The future itself is at stake.