Gotham’s resident baddies are back in action! Join Harley Quinn, Catwoman, and Poison Ivy as they take on a new threat facing the city they call home—the alien despot Despero! When a new space-themed club opens in Gotham, the girls quickly discover that something nefarious might be going on under the flashing lights and thumping bass, but they soon find themselves in the crosshairs of a conspiracy of cosmic proportions!

Collects Gotham City Sirens: Unfit for Orbit #1-5, the entire event series written by Leah Williams and drawn by Haining!