Disc: 1
1. Cross Road Blues - Robert Johnson
2. That's All Right - Arthur Crudup
3. The Blues Had a Baby and They Named It Rock and Roll - Muddy Waters
4. Need Your Love so Bad - Fleetwood Mac
5. Lovin' in My Baby's Eyes - Taj Mahal
6. I'm Your Hoochie Coochie Man - Willie Dixon
7. Death Letter Blues - Son House
8. Whiskey Headed Blues - Sonny Boy Williamson
9. Crying in My Sleep - Jimmy Yancey
10. Muddy Water (A Mississippi Moan) - Bessie Smith
11. Motherless Children - Blind Willie Johnson
12. Fort Worth and Dallas Blues - Leadbelly
13. I'm Gonna Train My Baby - Robert Lockwood
14. Seminole Blues - Tampa Red
15. Johnny B. Goode - Johnny Winter
16. Got My Mojo Workin' - Otis Spann
17. River of No Return - The Jeff Healey Band

Disc: 2
1. Blues for Mama - Nina Simone
2. Pride and Joy - Stevie Ray Vaughan & Double Trouble
3. Killing Floor - The Electric Flag
4. I'd Rather Go Blind - Chicken Shack
5. Early in the Morning - Bill Gillum
6. Give Me an Old, Old Lady - Bukka White
7. Baby, Please Don't Go - Big Joe Williams
8. Stormy Monday Blues - Earl Hines & His Orchestra
9. That Ain't Right - Mildred Bailey
10. Sunny Road - Roosevelt Sykes
11. Bumble Bee Blues - Memphis Jug Band
12. Worried Life Blues - Big Maceo Merriweather
13. Confessin' the Blues - Jimmy Witherspoon With Jay McShann And His Band
14. No More Women Blues - Lonnie Johnson
15. When the Sun Goes Down - Leroy Carr
16. Honky Tonk Train Blues - Meade 'Lux' Lewis
17. Beer Drinkin' Woman - Memphis Slim

Disc: 3
1. Hard to Be - The Vaughan Brothers
2. Sawbuk - Top Topham
3. Cleanhead Blues - Eddie "Cleanhead" Vinson
4. Hold Me (Just a Little Longer Tonight) - Etta James
5. Baby Don't You Think I Know - Johnny Shines
6. Everyday I Have the Blues - Joe Williams
7. Broke and Hungry Blues - Big Maceo
8. Prowling Night Hawk - Robert Lee McCoy
9. Deep Down in the Ground - Sonny Boy Williamson
10. Rag Mama Rag - Blind Boy Fuller
11. I Love My Baby - Tommy McClennan
12. Mean Old Frisco Blues - Arthur Crudup
13. Sweet Home Chicago - Robert Johnson
14. Careless Love - Joe Turner
15. Friendless Blues - Big Bill Broonzy
16. She's Makin' a Fool Out of Me - Leroy Bachelor, Robert Brown, Washboard Sam & His Washboard Band
17. Billie's Blues (I Love My Man) - Billie Holiday, Billie Holiday & Her Orchestra

Disc: 4
1. Howling Wolf - Muddy Waters
2. I've Got to Forget You - Jellybread
3. Corinna - Taj Mahal
4. Let Me Miss You, Baby - Henry 'Red' Allen
5. Back O' Town Blues - Louis Armstrong & His All Stars
6. Rocks in My Bed - Duke Ellington & His Famous Orchestra
7. Brand New Wagon - Count Basie & His Orchestra
8. St. Louis Blues - Jack Teagarden's Big Eight
9. The Blues in My Flat - Benny Goodman Quartet
10. Why Don't You Do Right? (Get Me Some Money Too) - Lil Green
11. Kassie Jones, Pt. 1 - Furry Lewis
12. Wipe It Off - Lonnie Johnson
13. Southern Can Is Mine - Blind Sammie, Blind Willie McTell
14. Key to the Highway 70 No. 1 - Brownie McGhee
15. Lend Me Your Love - Memphis Slim
16. Am I Wrong - Keb' Mo'
17. JB's Blues - Jeff Beck, Tony Hymas